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Modulation of thermal stability can enhance the potency of siRNA. Addepalli H, Meena, Peng CG, Wang G, Fan Y, Charisse K, Jayaprakash KN, Rajeev KG, Pandey RK, Lavine G, Zhang L, Jahn-Hofmann K, Hadwiger P, Manoharan M, Maier MA. Nucleic Acids Research. 2010; 38(20), 7320-7331. View Abstract on PubMed

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Polyethylenimine/small interfering RNA-mediated knockdown of vascular endothelial growth factor in vivo exerts anti-tumor effects synergistically with Bevacizumab. Hoebel S, Koburger I, John M, Czubayko F, Hadwiger P, Vornlocher HP, Aigner A. Journal of Gene Medicine. 2010; 12(3), 287-300. View Abstract on PubMed