Integrated CRDMO Services for Nucleic Acid Therapeutics
Single-source platform offering bioanalytics (mRNA and oligonucleotides), process development, and GMP manufacturing for RNA therapeutics
Core Focus
Identification and discovery of therapeutic oligonucleotides and mRNAs using bioinformatics-driven design, in silico modeling, and early in vitro screening.
Expertise
Proprietary sequence selection algorithms, RNA-Seq-based off-target analysis, and high-throughput screening to optimize lead candidates. Our Kulmbach facility’s deep bioinformatics platform and multiplex screening accelerate candidate validation, minimize risks, and prioritize high-potential leads.
Impact
Speeds early-stage development, reducing attrition by ensuring lead candidates are chemically optimized and biologically validated.
Core Focus
Conducting preclinical safety, pharmacokinetics, and biodistribution studies, with robust bioanalysis to support IND/CTA submissions.
Expertise
GLP-compliant bioanalysis, LC-MS/MS assays, and advanced cell-based functional testing for comprehensive data packages.
Impact
Delivers regulatory-aligned data, streamlines toxicology and immunogenicity evaluations, and ensures a smooth path to clinical trials.
Core Focus
Non-GMP manufacturing, process development, and synthesis scale-up for toxicology studies, bridging the gap between discovery and clinical readiness.
Expertise
High-throughput synthesis of modified oligonucleotides and their conjugates, advanced impurity profiling, and validated in-process controls.
Impact
Enables efficient scale-up, technical validation, and seamless transfer to GMP production by de-risking manufacturing processes early.
Core Focus
GMP-certified production of small RNA-based (ex. siRNA, ASO, sgRNA, aptamer) therapeutics, ensuring consistent supply for Phase I–III and commercial pipelines.
Expertise
Globally resilient manufacturing sites in Petaluma and Berlin leveraging high-capacity synthesis and purification platforms, and end-to-end analytical support.
Impact
Ensures large-scale, high-purity output with global regulatory compliance, enabling a reliable supply for clinical trials and commercial launch.
Meet us
Get to know the team behind Axolabs, where innovation meets collaboration. Meet the scientists, technical experts, and industry leaders dedicated to advancing oligonucleotide therapeutics and delivering excellence at every stage of development.
Join us
Join a global leader in oligonucleotide research and development. At Axolabs, you’ll work with state-of-the-art technologies, collaborate with world-class experts, and contribute to shaping the future of nucleic acid therapeutics. Explore career opportunities today.