Manufacturing of Gene Editing Oligonucleotides

We offer:

  • Solid phase synthesis of therapeutic sgRNAs
  • Variety of chemical modalities
  • Scalable manufacturing process in mg to multigram quantities (nonGMP/GMP)
  • Unprecedented purity 
  • Methods established to achieve up to 150-nt long sgRNA synthesis
  • Long RNA synthesis
    • Peptide-conjugated long RNAs
    • Long RNAs with 5’-triphosphate 
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