PNA-HPLC assay
Axolabs has a unique and proprietary assay system for the sensitive detection of oligonucleotides from biological matrices.
- Assay established in regulated environment (GLP/GCP), support from early development up to Clinical Phase 2 trials
- Extraction-free and robust procedure with the option of parallel detection of multiple analytes
- Assay compatible with conjugates and different oligonucleotide chemistries
- Simultaneous detection of metabolites
- Detection of 5’-phosphorylation of siRNAs as a marker for cytoplasmic delivery